In a special supplement to the *Journals of Gerontology, Series B*, Robert Schoeni, Vicki Freedman, and Kenneth Langa introduce an examination of dementia across the US. Emanating from an NIA-funded 2017 workshop, the nine featured papers in this supplement provide important new evidence on the prevalence, disparities, and trends in Alzheimer’s disease and other related dementias among older Americans.

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