The Michigan Institute for Data Science invites proposals for projects that will advance the methodological foundations of data science in the health and social sciences. Up to two projects will be funded at about $1.25 million each. Town hall meetings to explain award competition and project support are scheduled for March 9 and 10; March 30 and 31. White papers describing the project goals and teams are due May 16. Full proposals are due September 12. Awards will be announced on October 10.