Kenneth Langa and co-authors publish in JAMA on association of lifestyle and genetic risk with incidence of dementia. The study included 196 383 participants of European ancestry aged at least 60 years without dementia at baseline. They concluded “participants with a high genetic risk and unfavorable lifestyle score had a statistically significant hazard ratio for incident all-cause dementia of 2.83 compared with participants with a low genetic risk and favorable lifestyle score. A favorable lifestyle was associated with a lower risk of dementia and there was no significant interaction between genetic risk and healthy lifestyle.”

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